Hydrogen Bond Interactions of Nucleobases: A Quick Review





Hydrogen bond, Interaction, Nucleobase, DFT, DNA, RNA


Hydrogen bond (HB) interactions in nucleobases; Adenine (A), Guanine (G), Cytosine (C), Thymine (T), and Uracil (U), were discussed quickly in this review work. The features of HB interactions were already investigated by the means of computer-based works and experiments. Formations of homo and hetero complexes of nucleobases through HB interactions could be characterizations using obtained parameters from X-ray, NMR and NQR techniques. Such spectroscopic properties could be evaluated by both of computations and experiments. Indeed, structural refinement could be also done by computations, in which more reliable results could be provided for further investigations. In addition to original nucleobases, their modified structures could also work their roles especially in medications. Due to such importance of the topic, the features of HB interactions in nucleobases were discussed in this quick review.


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How to Cite

Mirzaei, M. (2020). Hydrogen Bond Interactions of Nucleobases: A Quick Review. Lab-in-Silico, 1(2), 61–66. https://doi.org/10.22034/labinsilico20012061



Review Article